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✓ Fact-checked by Dr. Marisol Aguilar, PharmD · ✎ Written by AlkaLean Editorial Team · 📅 Updated July 2026
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Guide  ·  July 2026  ·  6 min read  ·  Fact-checked by Dr. Marisol Aguilar, PharmD

CFU Counts: The Question To Ask Before Buying

If you take one practical skill from this site, make it this one. It applies to every probiotic product you will ever consider, not just this one.

What CFU Means

Colony-forming units — the count of viable bacteria capable of reproducing. It's the standard measure of probiotic potency, and it's what clinical trials specify when they report a dose.

A typical probiotic trial might use 1 billion, 10 billion, or 50 billion CFU daily. Those are the numbers the research is built on.

Why Milligrams Tell You Almost Nothing

A probiotic label giving only a weight — "probiotic blend 35 mg" — is describing the mass of powder in the capsule, not the number of living organisms in it.

Those are wildly different things. Freeze-dried bacterial powders vary enormously in cell density depending on the strain, the drying process, the carrier used and how the product has been stored. The same 35 mg could contain a hundred million viable cells or a few million.

There's no conversion you can do at home. Weight cannot be translated into CFU without knowing the specific preparation. If a label gives you only milligrams, you genuinely do not know what you are buying — and that's true regardless of how good the strain selection looks.

Why Viability Is Fragile

Probiotics are living organisms, and manufacturing is hostile to them: heat, moisture, oxygen, time on a shelf, then stomach acid. Some strains survive that far better than others — spore-formers particularly — while anaerobes like Akkermansia muciniphila are oxygen-sensitive and technically harder to keep viable.

That's why CFU is usually specified "at time of manufacture" or, better, "at expiry." The second is the more honest figure, and the one worth asking for.

Exactly What To Ask

Email the brand before ordering. Four questions, all reasonable:

  1. What is the CFU count per strain, not just for the blend?
  2. Is that count at time of manufacture, or guaranteed through expiry?
  3. What preparation is used — live, freeze-dried, pasteurised?
  4. How should it be stored to maintain viability?

How To Read The Answer

A company confident in its sourcing will usually answer these directly, and quickly. A vague answer, a deflection to "proprietary information," or no reply at all is itself information — not proof of anything wrong, but a reasonable input into your decision.

Where AlkaLean Stands

AlkaLean names all three strains individually, which is better than a generic "probiotic blend" description. It publishes the blend weight at 35 mg. It does not publish CFU counts anywhere reviewed.

That's a real gap for a probiotic-containing product, and it's the single most useful thing to resolve before ordering. Our contact page lists what else is worth asking at the same time.

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